Soda may Aceelerate Aging Doctors say

Drinking Soda May Accelerate Aging

Posted on 2010-05-26 06:00:00 in

Lifestyle |

Longevity |

Nutrition |

Drinking Soda May Accelerate Aging

New research suggests that drinking sodas and eating processed
foods, both of which contain high levels of phosphates may accelerate
the aging process. M. Shawkat Razzaque, M.D., Ph.D., from the Department
of Medicine, Infection and Immunity at the Harvard School of Dental
Medicine (US), and Mutsuko Ohnishi from the Department of Pathology,
Nagasaki University Graduate School of Biomedical Sciences (Japan),
studied the effects of high phosphate levels in three groups of mice.
The first group was missing a gene (klotho), which when absent, causes
mice to have toxic levels of phosphate in their bodies. These mice lived
for 8 to 15 weeks. The second group was missing the klotho gene and a
second gene (NaPi2a), which when absent at the same time, substantially
lowered the amount of phosphate in their bodies. These mice lived to 20
weeks. The third group, like the second group, was missing both the
klotho and NaPi2a genes, but was also fed a high-phosphate diet. Like
the mice in the first group, all of the mice in the third group died by
15 weeks. Thus suggesting that phosphate has toxic effects in mice, and
raising the possibility that it may have a similar effect in humans.
Further investigations revealed that high levels of phosphates
accelerate signs of aging, and may also increase the prevalence and
severity of age-related complications, such as chronic kidney disease
and cardiovascular calcification, as well as inducing severe muscle and
skin atrophy. "Humans need a healthy diet and keeping the balance of
phosphate in the diet may be important for a healthy life and
longevity," said Dr Razzaque. "Avoid phosphate toxicity and enjoy a
healthy life."

Drinking Soda May Accelerate AgingMutsuko Ohnishi, M Shawkat Razzaque. Dietary and genetic evidence for
phosphate toxicity accelerating mammalian aging. FASEB J. 2010 Apr 23.
The Journal of The Federation of American Societies for Experimental Biology


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